BDBM249017 US9434725, 248
SMILES C[C@]1(O)CNCCN(C1)c1cccc(n1)-n1ncc2cnc(cc12)-c1cnn(CC(F)(F)F)c1
InChI Key InChIKey=GXDSAAYOXDQSQT-NRFANRHFSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 249017
Affinity DataKi: 1.64nM ΔG°: -12.0kcal/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Affinity DataKi: 3.36nM ΔG°: -11.6kcal/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Affinity DataKi: 22.1nM ΔG°: -10.4kcal/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair