BDBM249056 US9434725, 287
SMILES O=c1cncc([nH]1)-c1cc2n(ncc2cn1)-c1cccc(n1)N1CCNCC1
InChI Key InChIKey=GNAXCGUONRASLS-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 249056
Affinity DataKi: 0.370nM ΔG°: -12.9kcal/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Affinity DataKi: 0.698nM ΔG°: -12.5kcal/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Affinity DataKi: 17.5nM ΔG°: -10.6kcal/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair