BDBM24934 2-amino-isoxazolopyridine, 13::3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}pyrido[4,3-d][1,2]oxazol-3-yl)phenyl]propan-1-ol

SMILES C[C@H](Nc1cc2c(noc2cn1)-c1cc(Cl)cc(CCCO)c1)c1ccccc1

InChI Key InChIKey=MMGKIHLBFPJYJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24934   

TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24934(3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}pyrido...)
Affinity DataIC50: 99nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed