Molecular Structure for 24997

oxadiazole-containing compound, 10 4-[7-(3-aminopropoxy)-1-ethyl-4-phenyl-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine

Data: 3 IC50

Vconf -m prep

Found 3 hits in this search
Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Ribosomal S6 Kinase 1 (RSK-1) Homo sapiens (human)	oxadiazole-containing compound, 10 (4-[7-(3-aminopropoxy)-1-ethyl-4-phenyl-1H-imidazo[...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	44.0	n/a	n/a	7.2	30
GlaxoSmithKline			CSLS PC cid PC sid	PubMed	J Med Chem. 51: 5663-79 (2008)
Mitogen- and Stress-Activated Protein Kinase 1 (MSK1) Homo sapiens (human)	oxadiazole-containing compound, 10 (4-[7-(3-aminopropoxy)-1-ethyl-4-phenyl-1H-imidazo[...)	DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	1000.0	n/a	n/a	7.5	30
GlaxoSmithKline			CSLS PC cid PC sid	PubMed	J Med Chem. 51: 5663-79 (2008)
Protein kinase B (Akt 1) Homo sapiens (human)	oxadiazole-containing compound, 10 (4-[7-(3-aminopropoxy)-1-ethyl-4-phenyl-1H-imidazo[...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	331.0	n/a	n/a	7.5	22
GlaxoSmithKline			CSLS PC cid PC sid	PubMed	J Med Chem. 51: 5663-79 (2008)