BDBM250045 US10005782, Compound 167::US9447106, 167::US9556188, Compound 167

SMILES COc1cc(cc(OC)c1OC)-c1nn2C(CCNc2c1C(N)=O)c1ccccc1NC(=O)C=C

InChI Key InChIKey=LPFFQSHDXZSJSR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 250045   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM250045(US10005782, Compound 167 | US9447106, 167 | US9556...)
Affinity DataIC50:  2.40nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM250045(US10005782, Compound 167 | US9447106, 167 | US9556...)
Affinity DataIC50:  2.40nMAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM250045(US10005782, Compound 167 | US9447106, 167 | US9556...)
Affinity DataIC50:  2.40nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent