BDBM250277 US10501411, Example 187::US11697636, Example 187::US9452980, 187
SMILES Clc1ccc(cc1)C(=O)Nc1ccc(cn1)C1CCCNC1
InChI Key InChIKey=COFTYTLVJXMKLZ-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 250277
Affinity DataKi: 12.3nM ΔG°: -11.2kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...More data for this Ligand-Target Pair
Affinity DataKi: 12.3nMAssay Description:Rat: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentr...More data for this Ligand-Target Pair
Affinity DataKi: 12.3nMAssay Description:The TAAR1 radioligand 3[H]—(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration...More data for this Ligand-Target Pair