BDBM25036 CHEMBL393525::N'-[(1E)-{6-bromoimidazo[1,2-a]pyridin-3-yl}methylidene]-N,2-dimethyl-5-nitrobenzene-1-sulfonohydrazide::PIK-75, 1::US10981896, Compound PIK75::imidazopyridine derivative, 8c

SMILES: Cc1ccc(cc1S(=O)(=O)N(C)/N=C/c2cnc3n2cc(cc3)Br)[N+](=O)[O-]

InChI Key: InChIKey=QTHCAAFKVUWAFI-UHFFFAOYSA-N

Data: 32 IC50  6 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 40 hits for monomerid = 25036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0560	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 7 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	850	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
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Putative glycogen synthase kinase 3 alpha (Corn smut fungus)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Casein kinase I isoform epsilon (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	405	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK2 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK3 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK4 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 3 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 4 (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair