BDBM25120 5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-{[2-(trifluoromethyl)phenyl]methoxy}thiophene-2-carboxamide::BMCL191018 Compound 2::thiophene deriv., 20

SMILES: COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(s3)C(N)=O)c2cc1OC

InChI Key: InChIKey=JSKUWFIZUALZLX-UHFFFAOYSA-N

Data: 4 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 25120   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	7.2	22
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Serine/threonine-protein kinase PLK3 (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	7.2	22
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Serine/threonine-protein kinase PLK1 (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK3 (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK2 (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		4.80	-11.2	n/a	n/a	n/a	n/a	n/a	7.5	22
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK3 (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK4 (Human)	BDBM25120 (BMCL191018 Compound 2 | 5-(5,6-dimethoxy-1H-1,3-be...) Show SMILES Show InChI	GoogleScholar	UniChem		163	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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