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BDBM25135 2-cyano-pyrropyrimidine, 7a::7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl)-2-fluorophenoxymethyl]-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile

SMILES: CC(=O)N1CCN(CC1)c1ccc(OCc2cc3cnc(nc3n2CCC2CCCCC2)C#N)c(F)c1

InChI Key: InChIKey=RKKQUNNKTWJTLY-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 25135   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cathepsin S


(Human)		BDBM25135
PNG
(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)		GoogleScholar
UniChem
n/an/a 18n/an/an/an/a7.022


TBA



Citation and Details
More data for this
Ligand-Target Pair
Cathepsin S


(Mouse)		BDBM25135
PNG
(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)		GoogleScholar
UniChem
n/an/a 14n/an/an/an/a7.022


TBA



Citation and Details
More data for this
Ligand-Target Pair
Cathepsin K


(Human)		BDBM25135
PNG
(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)		GoogleScholar
UniChem
n/an/a 5.90E+3n/an/an/an/a7.022


TBA



Citation and Details
More data for this
Ligand-Target Pair
Cathepsin K


(Rat)		BDBM25135
PNG
(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)		GoogleScholar
UniChem
n/an/a>1.00E+4n/an/an/an/a7.022


TBA



Citation and Details
More data for this
Ligand-Target Pair
Procathepsin L


(Human)		BDBM25135
PNG
(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)		GoogleScholar
UniChem
n/an/a 6.80E+3n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Procathepsin L


(Rat)		BDBM25135
PNG
(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)		GoogleScholar
UniChem
n/an/a>1.00E+4n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair