BDBM251460 US9452998, 9

SMILES: CC1(N)CCN(CC1)c1cccnc1NC(=O)c1nc(cnc1N)-c1ncccc1C(F)(F)F

InChI Key: InChIKey=XXJXHXJWQSCNPX-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 251460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C alpha type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
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Protein kinase C theta type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.4	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	7.0	25
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Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Protein kinase C theta type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C alpha type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C eta type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C beta type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C beta type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C gamma type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C delta type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C epsilon type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM251460 (US9452998, 9) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair