BDBM25198 3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methylphenol::6-substituted 4-anilinoquinoline, 38

SMILES: Cc1ccc(cc1Nc2ccnc3c2cc(cc3)S(=O)(=O)C)O

InChI Key: InChIKey=BVHZLDLRNBQWRF-UHFFFAOYSA-N

Data: 5 KI  12 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 25198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	775	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	775	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	22
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Mitogen-activated protein kinase 14 (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-interacting serine/threonine-protein kinase 2 (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-interacting serine/threonine-protein kinase 2 (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		588	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		588	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM25198 (3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair