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BDBM252704 US9458176, 101

SMILES: CCc1ccc(cc1OC)-c1nc(c2CCO[C@H](C)Cn12)-c1ccnc(C)c1

InChI Key: InChIKey=GBXBLCKGNHBAHJ-XISACWJONA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 252704   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM252704
PNG
(US9458176, 101)
Show SMILES CCc1ccc(cc1OC)-c1nc(c2CCO[C@H](C)Cn12)-c1ccnc(C)c1
Show InChI InChI=1/C23H27N3O2/c1-5-17-6-7-19(13-21(17)27-4)23-25-22(18-8-10-24-15(2)12-18)20-9-11-28-16(3)14-26(20)23/h6-8,10,12-13,16H,5,9,11,14H2,1-4H3/t16-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 7.60n/an/an/an/an/a25



Eisai R&D Management Co., Ltd

US Patent


Assay Description
The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...


US Patent US9458176 (2016)


BindingDB Entry DOI: 10.7270/Q2PK0F3D
More data for this
Ligand-Target Pair