BDBM25279 BPH-608::bisphosphonate, 31::{1-hydroxy-2-[3-(3-phenylphenyl)phenyl]-1-phosphonoethyl}phosphonic acid
SMILES OC(Cc1cccc(c1)-c1cccc(c1)-c1ccccc1)(P(O)(O)=O)P(O)(O)=O
InChI Key InChIKey=YXQQNSYZOQHKHD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 25279
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University Of California San Diego
University Of California San Diego
Affinity DataIC50: 1.80E+4nMpH: 7.5Assay Description:We screened an in-house library of 53 compounds using trans-FPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by ...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataIC50: 2.14E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair