BDBM25313 (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid::Alendronate::CHEMBL870::bisphosphonate, 65

SMILES: C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN

InChI Key: InChIKey=OGSPWJRAVKPPFI-UHFFFAOYSA-N

Data: 6 KI  10 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 25313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl pyrophosphate synthase (Human)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.37E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.75E+7	n/a	n/a	n/a	n/a	7.4	37
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Farnesyl pyrophosphate synthase (Human)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Geranylgeranyl pyrophosphate synthase (Human)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	955	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		44.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Leishmania major)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Polyprenyl synthetase family protein (Leishmania donovani)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		393	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Hypoxanthine-guanine phosphoribosyltransferase (Trypanosoma brucei brucei)	BDBM25313 ((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...) Show SMILES Show InChI	GoogleScholar	UniChem		1.89E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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