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BDBM253153 US9458171, 113

SMILES: Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)c1ccncc1)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=NCJPRDUCVPEPHV-QFIPXVFZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 253153   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM253153
PNG
(US9458171, 113)
Show SMILES Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)c1ccncc1)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C25H18F8N2O3S/c26-19-5-7-20(8-6-19)39(37,38)22(11-14-35(15-22)21(36)16-9-12-34-13-10-16)17-1-3-18(4-2-17)23(27,24(28,29)30)25(31,32)33/h1-10,12-13H,11,14-15H2/t22-/m0/s1
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 287n/an/an/an/an/a25



Bristol-Myers Squibb Co.

US Patent


Assay Description
The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintill...


US Patent US9458171 (2016)


BindingDB Entry DOI: 10.7270/Q2NK3CZM
More data for this
Ligand-Target Pair