BDBM253928 US10189849, Compound 27::US10927120, Compound 27::US9464092, T::US9527857, T::US9957276, Compound 27

SMILES: CN1CCN(CC1)c1ccc(Nc2ncc3cc4C(=O)NCC5(CCCCC5)n4c3n2)nc1

InChI Key: InChIKey=PDGKHKMBHVFCMG-UHFFFAOYSA-N

Data: 19 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 253928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.67	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-dependent kinase 2 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.821	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.64	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.66	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.821	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM253928 (US9464092, T | US9527857, T | US10189849, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair