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BDBM254064 US9493430, 739

SMILES: C[C@H]1[C@H](OC(=O)N1CC1=C(CCC(C)(C)C1)c1cc(ccc1F)-c1ccc(cc1Cl)C(O)=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=OCGPVGXQMOJEMC-KAPMGQBHNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254064   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))
BDBM254064
PNG
(US9493430, 739)
Show SMILES C[C@H]1[C@H](OC(=O)N1CC1=C(CCC(C)(C)C1)c1cc(ccc1F)-c1ccc(cc1Cl)C(O)=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1/C34H29ClF7NO4/c1-17-29(20-10-22(33(37,38)39)14-23(11-20)34(40,41)42)47-31(46)43(17)16-21-15-32(2,3)9-8-24(21)26-12-18(5-7-28(26)36)25-6-4-19(30(44)45)13-27(25)35/h4-7,10-14,17,29H,8-9,15-16H2,1-3H3,(H,44,45)/t17-,29-/s2
PDB
MMDB

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KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 20.3n/an/an/an/an/an/a



Chong Kun Dang Pharmaceutical Corp.

US Patent


Assay Description
As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...


US Patent US9493430 (2016)


BindingDB Entry DOI: 10.7270/Q2W37V7V
More data for this
Ligand-Target Pair