BDBM254266 US10112937, Example 158::US10150765, Example 158::US10703749, Example 158::US9464084, 158

SMILES: C[C@H]1N(CCc2c1nnn2-c1ncc(F)cn1)C(=O)c1cccc(c1Cl)C(F)(F)F

InChI Key: InChIKey=CWFVVQFVGMFTBD-UHFFFAOYSA-N

Data: 12 KI  25 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 37 hits for monomerid = 254266   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 3A4 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 7 (Rat)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 7 (Mouse)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rat)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rat)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18.8	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Mouse)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rat)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
P2X purinoceptor (Rhesus macaque)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rat)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18.8	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 2C8 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rat)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18.8	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rat)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rat)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rat)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rat)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rat)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rat)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rat)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Human)	BDBM254266 (US9464084, 158 | US10112937, Example 158 | US10150...) Show SMILES Show InChI	GoogleScholar	UniChem		9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair