BDBM25513 1-(3-methanesulfonylphenyl)-3-methyl-N-[(1S)-1-phenylethyl]-1H-pyrazolo[4,3-c]pyridin-6-amine::2-amino-pyrazolopyridine, 19

SMILES C[C@H](Nc1cc2n(nc(C)c2cn1)-c1cccc(c1)S(C)(=O)=O)c1ccccc1

InChI Key InChIKey=FPYKYTAARCRYBS-HNNXBMFYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25513   

TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM25513(1-(3-methanesulfonylphenyl)-3-methyl-N-[(1S)-1-phe...)
Affinity DataIC50:  225nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed