BDBM255338 US9481682, 116::US9481682, 88

SMILES: COc1cc(ccc1-c1nc([C@@H]2CC[C@H]3CCC(=O)N3C2)n2ccnc(N)c12)C(=O)Nc1cc(ccn1)C(F)(F)F

InChI Key: InChIKey=OMIQRSKHABIPRH-UHFFFAOYSA-N

Data: 20 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 255338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase FRK (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Yes (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase TXK (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Tec (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Srms (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
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Protein-tyrosine kinase 6 (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fyn (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fgr (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-4 (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase CSK (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	227	n/a	n/a	n/a	n/a	n/a	n/a
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Cytoplasmic tyrosine-protein kinase BMX (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Blk (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM255338 (US9481682, 88 | US9481682, 116) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
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