BDBM25558 4-arylamino-3-pyridinecarbonitrile, 4p::5-(3,4-dimethoxyphenyl)-4-(1H-indol-5-ylamino)pyridine-3-carbonitrile::BMCL192461 Compound 1a::CHEMBL492251
SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1
InChI Key InChIKey=KPDRLZMGHJWHQC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 25558
Affinity DataKi: 79nM ΔG°: -9.58kcal/mole IC50: 70nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human PKCtheta by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of human PKCdelta by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair