BDBM257194 US9493440, 38

SMILES CC1(CC1)Oc1ccc2[nH]nc(-c3cc(ncn3)N3CCC4(CNC(=O)C4)CC3)c2c1

InChI Key InChIKey=SBJWDHBUWTYDBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 257194   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [970-2527,G2019S](Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM257194(US9493440, 38)
Affinity DataIC50:  5.10nMpH: 8.5 T: 2°CAssay Description:a) 400 nl of a 1:2.15 serial dilution of test compound (98 uM top assay concentration) is spotted via Labcyte Echo to certain wells in a 384 well bla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [970-2527,G2019S](Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM257194(US9493440, 38)
Affinity DataIC50: <0.600nMpH: 8.5 T: 2°CAssay Description:a) 400 nl of a 1:2.15 serial dilution of test compound (98 uM top assay concentration) is spotted via Labcyte Echo to certain wells in a 384 well bla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent