BDBM25729 1,3-bis(3,4-dichlorophenyl)urea::CHEMBL10835::US8815951, 299::Urea-based compound, 10
SMILES Clc1ccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)cc1Cl
InChI Key InChIKey=ZDPIZPXVHVYTOK-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 25729
Affinity DataIC50: 480nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:The invention also provide methods for assaying for epoxide hydrolase activity as diagnostic assay to identify individuals at increased risk for hype...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Colorado State University
Curated by ChEMBL
Colorado State University
Curated by ChEMBL
Affinity DataIC50: 28.1nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate assessed as appearance of 6-methoxy-2-naphthaldehyde after 10 mins...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Pennsylvania State University
Curated by ChEMBL
The Pennsylvania State University
Curated by ChEMBL
Affinity DataIC50: 708nMAssay Description:Inhibitory activity against murine soluble epoxide hydrolaseMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Colorado State University
Curated by ChEMBL
Colorado State University
Curated by ChEMBL
Affinity DataIC50: 257nMAssay Description:Inhibitory activity against human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:The invention also provide methods for assaying for epoxide hydrolase activity as diagnostic assay to identify individuals at increased risk for hype...More data for this Ligand-Target Pair