BDBM25748 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}ethyl)-1-phenylurea::ICI 89,406::ICI 89406

SMILES: OC(CNCCNC(=O)Nc1ccccc1)COc1ccccc1C#N

InChI Key: InChIKey=HTLWRKRZKFAAAH-UHFFFAOYSA-N

Data: 1 KI  8 Kd  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 25748   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-1 adrenergic receptor (Human)	BDBM25748 (ICI 89,406 | 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.24	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM25748 (ICI 89,406 | 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Human)	BDBM25748 (ICI 89,406 | 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Human)	BDBM25748 (ICI 89,406 | 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.331	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Human)	BDBM25748 (ICI 89,406 | 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.813	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM25748 (ICI 89,406 | 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Human)	BDBM25748 (ICI 89,406 | 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Human)	BDBM25748 (ICI 89,406 | 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM25748 (ICI 89,406 | 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM25748 (ICI 89,406 | 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Human)	BDBM25748 (ICI 89,406 | 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM25748 (ICI 89,406 | 3-(2-{[3-(2-cyanophenoxy)-2-hydroxypr...) Show SMILES Show InChI	GoogleScholar	UniChem		132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair