BDBM25759 CHEMBL723::Carvedilol::Coreg::Dilatrend::Eucardic::[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-methoxyphenoxy)ethyl]amine

SMILES: COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12

InChI Key: InChIKey=OGHNVEJMJSYVRP-UHFFFAOYSA-N

Data: 8 KI  22 IC50  4 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 34 hits for monomerid = 25759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 2 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug and toxin extrusion protein 1 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-glucuronosyltransferase 1A1 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-glucuronosyltransferase 1A1 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium channel subfamily K member 2 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium channel subfamily K member 2 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium channel subfamily K member 10 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium channel subfamily K member 10 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 1 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.76	n/a	n/a	n/a	7.4	37
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Toll-like receptor 4 (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.195	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Rat)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Rat)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Human)	BDBM25759 ([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		247	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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