BDBM25762 CHEMBL471::N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide::SOTALOL HYDROCHLORIDE::Sotalol::Sotalol,(+)::Sotalol,(-)::cid_66245

SMILES: CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1

InChI Key: InChIKey=ZBMZVLHSJCTVON-UHFFFAOYSA-N

Data: 6 KI  15 IC50  5 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 25762   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family C member 2 (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1/Beta-2/Beta-3 adrenergic receptor (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.02E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Bovine)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Bovine)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Dog)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1/Beta-2/Beta-3 adrenergic receptor (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Dog)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.93E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	7.4	37
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ATP-binding cassette sub-family C member 3 (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Dog)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bcl-2-like protein 11 (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.50E+5	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.91E+3	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Rat)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		339	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Albumin (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		354	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Rat)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1B (Rat)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM25762 (Sotalol,(-) | CHEMBL471 | cid_66245 | Sotalol,(+) ...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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