BDBM2578 US8507510, 1.57::US8507510, 1.58

SMILES C[C@@H](Nc1nc(Nc2ccc(c(C)c2)S(C)(=N)=O)ncc1Br)C(C)(C)O

InChI Key InChIKey=GKJRCQIJVHMRJB-RRSIMWOXSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 2578   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM2578(US8507510, 1.57 | US8507510, 1.58)
Affinity DataIC50:  7nMAssay Description:Kinase assay using either CDK1, CDK2 or VEGFR-2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM2578(US8507510, 1.57 | US8507510, 1.58)
Affinity DataIC50:  4nMAssay Description:Kinase assay using either CDK1, CDK2 or VEGFR-2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM2578(US8507510, 1.57 | US8507510, 1.58)
Affinity DataIC50:  8nMAssay Description:Kinase assay using either CDK1, CDK2 or VEGFR-2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM2578(US8507510, 1.57 | US8507510, 1.58)
Affinity DataIC50:  66nMAssay Description:Kinase assay using either CDK1, CDK2 or VEGFR-2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM2578(US8507510, 1.57 | US8507510, 1.58)
Affinity DataIC50:  4nMAssay Description:Kinase assay using either CDK1, CDK2 or VEGFR-2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM2578(US8507510, 1.57 | US8507510, 1.58)
Affinity DataIC50:  45nMAssay Description:Kinase assay using either CDK1, CDK2 or VEGFR-2.More data for this Ligand-Target Pair
In DepthDetails US Patent