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BDBM2580 K252a::methyl (15R,16S,18S)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6),7(27),8(13),9,11,20(25),21,23-nonaene-16-carboxylate

SMILES: COC(=O)[C@]1(O)C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13

InChI Key: InChIKey=KOZFSFOOLUUIGY-UHFFFAOYSA-N

Data: 2 KI  3 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 2580   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein kinase C beta type


(Rat)		BDBM2580
PNG
(methyl (15R,16S,18S)-16-hydroxy-15-methyl-3-oxo-28...)		GoogleScholar
UniChem
n/an/a 470n/an/an/an/a7.530


TBA



Citation and Details
More data for this
Ligand-Target Pair
Insulin receptor


(Human)		BDBM2580
PNG
(methyl (15R,16S,18S)-16-hydroxy-15-methyl-3-oxo-28...)		GoogleScholar
UniChem
n/an/a 210n/an/an/an/a7.422


TBA



Citation and Details
More data for this
Ligand-Target Pair
Insulin-like growth factor 1 receptor


(Human)		BDBM2580
PNG
(methyl (15R,16S,18S)-16-hydroxy-15-methyl-3-oxo-28...)		GoogleScholar
UniChem
n/an/a 470n/an/an/an/a7.422


TBA



Citation and Details
More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase kinase 2


(Human)		BDBM2580
PNG
(methyl (15R,16S,18S)-16-hydroxy-15-methyl-3-oxo-28...)		GoogleScholar
UniChem
 1.80n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Myosin light chain kinase, smooth muscle


(Human)		BDBM2580
PNG
(methyl (15R,16S,18S)-16-hydroxy-15-methyl-3-oxo-28...)		GoogleScholar
UniChem
 17n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair