BDBM2581 3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaen-12-one::CHEMBL16958::K-252c

SMILES: O=C1NCc2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21

InChI Key: InChIKey=MEXUTNIFSHFQRG-UHFFFAOYSA-N

Data: 26 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 2581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myosin light chain kinase, smooth muscle (Chicken)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit gamma (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
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O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Zinc finger protein GLI2 (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Zinc finger protein GLI1 (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Chymotrypsinogen B (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Malate dehydrogenase (Thermus thermophilus)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-lactamase (Escherichia coli (strain K12))	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C alpha/beta/delta/epsilon/eta/gamma/theta/zeta type (Rat)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-dependent protein kinase 1 (Bovine)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C beta type (Rat)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.5	30
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Rho-associated protein kinase 2 (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2 (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C theta type (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 11 (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 9 (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	138	n/a	n/a	n/a	n/a	7.2	37
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					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	830	n/a	n/a	n/a	n/a	7.0	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM2581 (CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	7.4	30
TBA									Citation and Details
					More data for this Ligand-Target Pair