BDBM2582 3,4-bis(1H-indol-3-yl)-1-methyl-2,5-dihydro-1H-pyrrole-2,5-dione::Bisindolylmaleimide deriv. 4::CHEMBL291725

SMILES: CN1C(=O)C(=C(C1=O)c1c[nH]c2ccccc12)c1c[nH]c2ccccc12

InChI Key: InChIKey=SWAWYMIKGOHZMR-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 2582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C beta type (Rat)	BDBM2582 (CHEMBL291725 | 3,4-bis(1H-indol-3-yl)-1-methyl-2,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
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cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM2582 (CHEMBL291725 | 3,4-bis(1H-indol-3-yl)-1-methyl-2,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.4	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM2582 (CHEMBL291725 | 3,4-bis(1H-indol-3-yl)-1-methyl-2,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM2582 (CHEMBL291725 | 3,4-bis(1H-indol-3-yl)-1-methyl-2,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM2582 (CHEMBL291725 | 3,4-bis(1H-indol-3-yl)-1-methyl-2,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM2582 (CHEMBL291725 | 3,4-bis(1H-indol-3-yl)-1-methyl-2,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM2582 (CHEMBL291725 | 3,4-bis(1H-indol-3-yl)-1-methyl-2,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM2582 (CHEMBL291725 | 3,4-bis(1H-indol-3-yl)-1-methyl-2,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair