BDBM17289 (1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-trien-14-one::CHEMBL1405::Estrone::Estrone (E1)::Estrone, 15::Estrovarin::Kestrone::Theelin::Unigen::[2,4,6,7-3H]-E1::[2,4,6,7-3H]-Estrone::folliculin

SMILES: C[C@]12CC[C@@H]3c4ccc(cc4CC[C@H]3[C@@H]1CCC2=O)O

InChI Key: InChIKey=DNXHEGUUPJUMQT-UHFFFAOYSA-N

Data: 4 KI  19 IC50  1 Kd  14 EC50

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 34 hits for monomerid = 17289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Steryl-sulfatase (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 1B1 (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sex hormone-binding globulin (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	218	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	29	n/a	166	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-synuclein (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	31	n/a	26	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	480	n/a	0.700	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.14E+3	n/a	2.10	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	7.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.940	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>10	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Corticosteroid-binding globulin (Human)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier organic anion transporter family member 1A1 (Rat)	BDBM17289 (folliculin | (1S,10R,11S,15S)-5-hydroxy-15-methylt...) Show SMILES Show InChI	GoogleScholar	UniChem		1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair