BDBM25849 4-[5-(4-hydroxyphenyl)thiophen-2-yl]phenol::CHEMBL204010::hydroxyphenyl substituted thiophene, 21
SMILES Oc1ccc(cc1)-c1ccc(s1)-c1ccc(O)cc1
InChI Key InChIKey=KZMOBYGIRBRCFV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 25849
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [125I]IMPY from beta amyloid plaque in brain homogenatesMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataEC50: 2.35E+3nMAssay Description:Agonist activity at estrogen receptor alpha (unknown origin) expressed in human HepG2 cells coexpressing estrogen response element after 24 hrs by lu...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataEC50: 1.54E+3nMAssay Description:Agonist activity at estrogen receptor beta (unknown origin) expressed in human HepG2 cells coexpressing estrogen response element after 24 hrs by luc...More data for this Ligand-Target Pair
Affinity DatapH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair