BDBM25897 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide::BMCL182567 Compound 6b::Diuredemina::Glomerulin::Hydroflumethiazide::cid_3647

SMILES: c1c(c(cc2c1NCNS2(=O)=O)S(=O)(=O)N)C(F)(F)F

InChI Key: InChIKey=DMDGGSIALPNSEE-UHFFFAOYSA-N

Data: 12 KI  6 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 25897   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family C member 4 (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein phosphatase non-receptor type 7 (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		305	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 14 (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		412	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 5B, mitochondrial (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		429	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 7 (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		433	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		435	-8.67	n/a	n/a	n/a	n/a	n/a	7.4	25
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Carbonic anhydrase 1 (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		2.84E+3	-7.56	n/a	n/a	n/a	n/a	n/a	7.4	25
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Carbonic anhydrase 4 (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		4.78E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 6 (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		8.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 5A, mitochondrial (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 13 (Mouse)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		1.54E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 3 (Human)	BDBM25897 (BMCL182567 Compound 6b | 1,1-dioxo-6-(trifluoromet...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+5	>-5.04	n/a	n/a	n/a	n/a	n/a	7.4	25
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