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BDBM2590 (Arylindolyl)maleimide deriv. 12::3-(1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::ROCHE screening, 40::bis-indolylmaleimide deriv. 8g

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc12

InChI Key: InChIKey=SEAKDKTVXBDRHV-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 2590   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein kinase C beta type


(Rat)		BDBM2590
PNG
(bis-indolylmaleimide deriv. 8g | 3-(1H-indol-3-yl)...)		GoogleScholar
UniChem
n/an/a 220n/an/an/an/a7.530


TBA



Citation and Details
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1


(Human)		BDBM2590
PNG
(bis-indolylmaleimide deriv. 8g | 3-(1H-indol-3-yl)...)		GoogleScholar
UniChem
n/an/a 1.25E+3n/an/an/an/a7.022


TBA



Citation and Details
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1


(Human)		BDBM2590
PNG
(bis-indolylmaleimide deriv. 8g | 3-(1H-indol-3-yl)...)		GoogleScholar
UniChem
n/an/a 1.95E+3n/an/an/an/an/a25


TBA



Citation and Details
More data for this
Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha


(Bovine)		BDBM2590
PNG
(bis-indolylmaleimide deriv. 8g | 3-(1H-indol-3-yl)...)		GoogleScholar
UniChem
n/an/a 1.17E+4n/an/an/an/an/a25


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase TBK1


(Human)		BDBM2590
PNG
(bis-indolylmaleimide deriv. 8g | 3-(1H-indol-3-yl)...)		GoogleScholar
UniChem
n/an/a 2.69E+3n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair