BDBM25901 4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-sulfamoylbenzamide::Indaflex::Indapamide::Indapamide (2)::Lozol::Noranat

SMILES: C[C@H]1Cc2ccccc2N1NC(=O)c3ccc(c(c3)S(=O)(=O)N)Cl

InChI Key: InChIKey=NDDAHWYSQHTHNT-UHFFFAOYSA-N

Data: 17 KI  6 IC50  42 Kd

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 65 hits for monomerid = 25901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 4 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	261	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 7 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 5B, mitochondrial (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 14 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 5B, mitochondrial (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 6 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 4 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 14 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	7.0	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	300	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	300	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	100	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.45E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 3 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 3 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Carbonic anhydrase 7 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM25901 (4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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