BDBM259200 US9499502, 29b
SMILES C[C@]1(CS(=O)(=O)C(C)(C)C(=N)N1)c1nc2ccc(cc2s1)-c1ccc(F)cc1
InChI Key InChIKey=UMINDAIWBBSGIP-FQEVSTJZSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 259200
Affinity DataKi: 300nM ΔG°: -9.04kcal/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
Affinity DataKi: 2.33E+3nM ΔG°: -7.81kcal/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair