BDBM259407 US10457647, Example 6::US11180460, Example 6::US11673868, Example 6::US9512084, 6

SMILES: CN(CCOc1c(N)ncnc1-c1cc(F)cc(NC(=O)c2ccc(cc2F)C2CC2)c1C)C(=O)C=C

InChI Key: InChIKey=CUABMPOJOBCXJI-UHFFFAOYSA-N

Data: 12 IC50  18 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 259407   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase TXK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Tec (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Epidermal growth factor receptor (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytoplasmic tyrosine-protein kinase BMX (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Blk (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-4 (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-4 (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Tec (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytoplasmic tyrosine-protein kinase BMX (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	30
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Bile salt export pump (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.48E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM259407 (US9512084, 6 | US10457647, Example 6 | US11180460,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair