BDBM259523 US9505749, 34
SMILES COc1ccc2[nH]c(=O)n(C3CCN(CC3)C(=O)CCCc3nc4ccccc4c(=O)[nH]3)c2c1
InChI Key InChIKey=MGEFDMCHHLACOB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 259523
Affinity DataIC50: 1.97nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Affinity DataIC50: 431nMAssay Description:PARP1 biochemical assay was purchased as a kit from Trevigen (cat.#4676-096-K) and used per manufacturers recommendations.PARP2 biochemical assay was...More data for this Ligand-Target Pair
Affinity DataIC50: 629nMAssay Description:PARP1 biochemical assay was purchased as a kit from Trevigen (cat.#4676-096-K) and used per manufacturers recommendations.PARP2 biochemical assay was...More data for this Ligand-Target Pair
Affinity DataIC50: 0.981nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair