BDBM259528 US9505749, 39
SMILES O=C(CCSc1nc2ccccc2c(=O)[nH]1)N[C@H]1C[C@H](C1)c1nnc(o1)-c1ccccc1
InChI Key
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 259528
Affinity DataIC50: 0.405nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:PARP1 biochemical assay was purchased as a kit from Trevigen (cat.#4676-096-K) and used per manufacturers recommendations.PARP2 biochemical assay was...More data for this Ligand-Target Pair
Affinity DataIC50: 0.389nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair