BDBM26018 4-({2-[(4-tert-butylphenyl)amino]-1H-1,3-benzodiazol-5-yl}oxy)-N-methylpyridine-2-carboxamide::arylaminobenzimidazole, 13

SMILES CNC(=O)c1cc(Oc2ccc3nc(Nc4ccc(cc4)C(C)(C)C)[nH]c3c2)ccn1

InChI Key InChIKey=DHMFGGZSCPEWEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26018   

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Novartis

LigandPNGBDBM26018(4-({2-[(4-tert-butylphenyl)amino]-1H-1,3-benzodiaz...)
Affinity DataIC50:  63nMAssay Description:To measure compound inhibitor effects on the ability of Raf enzymes to phosphorylate the Mek substrate, a capture ELISA utilizing streptavidin-coated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis

LigandPNGBDBM26018(4-({2-[(4-tert-butylphenyl)amino]-1H-1,3-benzodiaz...)
Affinity DataIC50:  15nMpH: 7.8 T: 2°CAssay Description:To measure compound inhibitor effects on the ability of Raf enzymes to phosphorylate the Mek substrate, a capture ELISA utilizing streptavidin-coated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed