BDBM260689 US9533985, 77
SMILES Cn1cnc2n(C)c(=O)n(-c3ccc(C[C@H](NC(=O)c4c(F)cc(NS(=O)(=O)c5ccc(cc5)-c5ncccn5)cc4F)C(O)=O)cc3)c(=O)c12
InChI Key InChIKey=WCPHBAWURXKJQA-VWLOTQADSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 260689
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 0.270nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1(Mus musculus (Mouse))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 9.10nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA...More data for this Ligand-Target Pair
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma
US Patent
Ea Pharma
US Patent
Affinity DataIC50: 150nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair