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BDBM260785 US9533989, 96

SMILES: N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc3n(Cc4ccc(cc4)-c4ccccc4)ccc23)n1

InChI Key: InChIKey=NYJQDEPKNUPOAZ-XTEPFMGCSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260785   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM260785
PNG
(US9533989, 96)
Show SMILES N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc3n(Cc4ccc(cc4)-c4ccccc4)ccc23)n1
Show InChI InChI=1S/C32H33N7O/c33-26-9-4-5-10-28(26)37-32-35-19-25(30(34)40)31(38-32)36-27-11-6-12-29-24(27)17-18-39(29)20-21-13-15-23(16-14-21)22-7-2-1-3-8-22/h1-3,6-8,11-19,26,28H,4-5,9-10,20,33H2,(H2,34,40)(H2,35,36,37,38)/t26-,28+/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 72.4n/an/an/an/an/an/a



Ziarco Pharma Ltd.

US Patent


Assay Description
The Promega ADP-Glo Kinase Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to mea...


US Patent US9533989 (2017)


BindingDB Entry DOI: 10.7270/Q2VQ31M7
More data for this
Ligand-Target Pair