BindingDB PrimarySearch_ki

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BDBM261686 US9708295, 27

SMILES: COc1cc(ncc1-c1cnc(N)c(O[C@H](C)c2c(Cl)ccc(F)c2Cl)c1)N1CCNC[C@@H]1C

InChI Key: InChIKey=BVGDAZBTIVRTGO-UHFFFAOYSA-N

Data: 2 KI 1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 261686
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ALK tyrosine kinase receptor (Human)	BDBM261686 (US9708295, 27) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM261686 (US9708295, 27) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Human)	BDBM261686 (US9708295, 27) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor [L1196M] (Human)	BDBM261686 (US9708295, 27) Show SMILES Show InChI	GoogleScholar	UniChem		35.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor [G1269S] (Human)	BDBM261686 (US9708295, 27) Show SMILES Show InChI	GoogleScholar	UniChem		61.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair