BDBM26210 (3S,6S,9aS)-6-[(2S)-2-aminopropanamido]-N-benzyl-5-oxo-octahydro-1H-pyrrolo[1,2-a]azepine-3-carboxamide::bicyclic Smac peptide mimetic, 4

SMILES C[C@H](N)C(=O)N[C@H]1CCC[C@H]2CC[C@H](N2C1=O)C(=O)NCc1ccccc1

InChI Key InChIKey=FHZYBAJOAPZBPA-HJWJTTGWSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26210   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University Of Michigan

LigandPNGBDBM26210((3S,6S,9aS)-6-[(2S)-2-aminopropanamido]-N-benzyl-5...)
Affinity DataKi:  150nM ΔG°:  -9.21kcal/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed