BDBM262187 3-(6-fluoropyridin-2-yl)-2- (2H-tetrazol-5- yl)benzenesulfonamide::US9708336, 36

SMILES NS(=O)(=O)c1cccc(-c2cccc(F)n2)c1-c1nn[nH]n1

InChI Key InChIKey=JCGDMKSFDTYZNJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262187   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262187(US9708336, 36 | 3-(6-fluoropyridin-2-yl)-2- (2H-te...)
Affinity DataIC50: 38.7nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
US Patent

TargetVIM-1 metallo-beta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262187(US9708336, 36 | 3-(6-fluoropyridin-2-yl)-2- (2H-te...)
Affinity DataIC50: 219nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
US Patent

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262187(US9708336, 36 | 3-(6-fluoropyridin-2-yl)-2- (2H-te...)
Affinity DataIC50: 790nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
US Patent