BDBM262190 3-pyrimidin-2-yl-2-(2H- tetrazol-5- yl)benzenesulfonamide::US9708336, 39

SMILES NS(=O)(=O)c1cccc(-c2ncccn2)c1-c1nn[nH]n1

InChI Key InChIKey=IFZAEOQZFRPOOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262190   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262190(US9708336, 39 | 3-pyrimidin-2-yl-2-(2H- tetrazol-5...)
Affinity DataIC50: 346nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
US Patent

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262190(US9708336, 39 | 3-pyrimidin-2-yl-2-(2H- tetrazol-5...)
Affinity DataIC50: 2.57E+3nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
US Patent

TargetVIM-1 metallo-beta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262190(US9708336, 39 | 3-pyrimidin-2-yl-2-(2H- tetrazol-5...)
Affinity DataIC50: 8.14E+3nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
US Patent