BDBM262245 3-(2-morpholin-4- ylpyrimidin-5-yl)-2-(2H- tetrazol-5- yl)benzenesulfonamide::US9708336, 94

SMILES NS(=O)(=O)c1cccc(-c2cnc(nc2)N2CCOCC2)c1-c1nn[nH]n1

InChI Key InChIKey=QGKUJJICKXDJAR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262245   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262245(3-(2-morpholin-4- ylpyrimidin-5-yl)-2-(2H- tetrazo...)
Affinity DataIC50:  164nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262245(3-(2-morpholin-4- ylpyrimidin-5-yl)-2-(2H- tetrazo...)
Affinity DataIC50:  234nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262245(3-(2-morpholin-4- ylpyrimidin-5-yl)-2-(2H- tetrazo...)
Affinity DataIC50:  6.32nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent