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BDBM26229 2-Aminopyrimidine analog., 4::4-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]benzonitrile::JMC516547 Compound 2

SMILES: CN1CCN(CC1)c1cc(nc(N)n1)-c1ccc(cc1)C#N

InChI Key: InChIKey=QFKQUMBUFVKQBH-UHFFFAOYSA-N

Data: 6 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 26229
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H4 receptor (Human)	BDBM26229 (4-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		35	-10.2	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM26229 (4-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		35	-10.2	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histamine H3 receptor (Rat)	BDBM26229 (4-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		245	-9.01	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histamine H4 receptor (Rat)	BDBM26229 (4-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		275	-8.94	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histamine H4 receptor (Rat)	BDBM26229 (4-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		275	-8.94	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM26229 (4-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		1.29E+3	-8.03	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair