BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM26230 2-Aminopyrimidine analog., 25::4-[2-amino-6-(piperazin-1-yl)pyrimidin-4-yl]benzonitrile::JMC516547 Compound 5

SMILES: Nc1nc(cc(n1)-c1ccc(cc1)C#N)N1CCNCC1

InChI Key: InChIKey=GXPQVRIHPFBPOG-UHFFFAOYSA-N

Data: 6 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 26230
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H4 receptor (Human)	BDBM26230 (4-[2-amino-6-(piperazin-1-yl)pyrimidin-4-yl]benzon...) Show SMILES Show InChI	GoogleScholar	UniChem		42	-10.1	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM26230 (4-[2-amino-6-(piperazin-1-yl)pyrimidin-4-yl]benzon...) Show SMILES Show InChI	GoogleScholar	UniChem		42	-10.1	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histamine H3 receptor (Rat)	BDBM26230 (4-[2-amino-6-(piperazin-1-yl)pyrimidin-4-yl]benzon...) Show SMILES Show InChI	GoogleScholar	UniChem		120	-9.43	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histamine H4 receptor (Rat)	BDBM26230 (4-[2-amino-6-(piperazin-1-yl)pyrimidin-4-yl]benzon...) Show SMILES Show InChI	GoogleScholar	UniChem		339	-8.82	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histamine H4 receptor (Rat)	BDBM26230 (4-[2-amino-6-(piperazin-1-yl)pyrimidin-4-yl]benzon...) Show SMILES Show InChI	GoogleScholar	UniChem		339	-8.82	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM26230 (4-[2-amino-6-(piperazin-1-yl)pyrimidin-4-yl]benzon...) Show SMILES Show InChI	GoogleScholar	UniChem		933	-8.22	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair