BDBM262654 3-((6-Amino-5-(hydroxymethyl)pyridin-3-yl)ethynyl)-2-(2H-tetrazol-5-yl)-6-(trifluoromethyl)benzenesulfonamide::US9708336, 507

SMILES Nc1ncc(cc1CO)C#Cc1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=RFBOCACISXANCN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262654   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262654(3-((6-Amino-5-(hydroxymethyl)pyridin-3-yl)ethynyl)...)
Affinity DataIC50:  4.31nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262654(3-((6-Amino-5-(hydroxymethyl)pyridin-3-yl)ethynyl)...)
Affinity DataIC50:  3.27nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262654(3-((6-Amino-5-(hydroxymethyl)pyridin-3-yl)ethynyl)...)
Affinity DataIC50:  11.5nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent